Luye Qin

Biochemistry, Neurobiology, Neurophysiology and Neuroscience.

Neurodevelopmental disorders and epilepsy.

Citations listed below are presented in a standardized, modified format for display purposes only. They do not necessarily reflect the preferred style and conventions of the faculty member or discipline.

Qin, Luye, Williams, J B., Tan, T, Liu, T, Cao, Q, Ma, K, and Yan, Z. Deficiency of autism risk factor ASH1L in prefrontal cortex induces epigenetic aberrations and seizures., 6589. Vol. 12, Iss. 1 Nature communications, 2021. (DOI: 10.1038/s41467-021-26972-8)
Qin, Luye, Ma, K, and Yan, Z. Rescue of histone hypoacetylation and social deficits by ketogenic diet in a Shank3 mouse model of autism.. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2021. (DOI: 10.1038/s41386-021-01212-1)
Rapanelli, M, Tan, T, Wang, W, Wang, X, Wang, Z J., Zhong, P, Frick, L, Qin, Luye, Ma, K, Qu, J, and Yan, Z. Behavioral, circuitry, and molecular aberrations by region-specific deficiency of the high-risk autism gene Cul3., 1491-1504. Vol. 26, Iss. 5 Molecular psychiatry, 2021. (DOI: 10.1038/s41380-019-0498-x)
Zhong, P, Qin, Luye, and Yan, Z. Dopamine Differentially Regulates Response Dynamics of Prefrontal Cortical Principal Neurons and Interneurons to Optogenetic Stimulation of Inputs from Ventral Tegmental Area., 4402-4409. Vol. 30, Iss. 8 Cerebral cortex (New York, N.Y. : 1991), 2020. (DOI: 10.1093/cercor/bhaa027)
Qin, Luye, Actor-Engel, H S., Woo, M S., Shakil, F, Chen, Y W., Cho, S, and Aoki, C. An Increase of Excitatory-to-Inhibitory Synaptic Balance in the Contralateral Cortico-Striatal Pathway Underlies Improved Stroke Recovery in BDNF Val66Met SNP Mice., 989-1002. Vol. 33, Iss. 12 Neurorehabilitation and neural repair, 2019. (DOI: 10.1177/1545968319872997)
Qin, Luye, Ma, K, and Yan, Z. Chemogenetic Activation of Prefrontal Cortex in Shank3-Deficient Mice Ameliorates Social Deficits, NMDAR Hypofunction, and Sgk2 Downregulation., 24-35. Vol. 17 iScience, 2019. (DOI: 10.1016/j.isci.2019.06.014)
Ma, K, Qin, Luye, Matas, E, Duffney, L J., Liu, A, and Yan, Z. Histone deacetylase inhibitor MS-275 restores social and synaptic function in a Shank3-deficient mouse model of autism., 1779-1788. Vol. 43, Iss. 8 Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018. (DOI: 10.1038/s41386-018-0073-1)
Wang, W, Rein, B, Zhang, F, Tan, T, Zhong, P, Qin, Luye, and Yan, Z. Chemogenetic Activation of Prefrontal Cortex Rescues Synaptic and Behavioral Deficits in a Mouse Model of 16p11.2 Deletion Syndrome., 5939-5948. Vol. 38, Iss. 26 The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. (DOI: 10.1523/JNEUROSCI.0149-18.2018)
Wei, J, Zhong, P, Qin, Luye, Tan, T, and Yan, Z. Chemicogenetic Restoration of the Prefrontal Cortex to Amygdala Pathway Ameliorates Stress-Induced Deficits., 1980-1990. Vol. 28, Iss. 6 Cerebral cortex (New York, N.Y. : 1991), 2018. (DOI: 10.1093/cercor/bhx104)
Qin, Luye, Ma, K, Wang, Z J., Hu, Z, Matas, E, Wei, J, and Yan, Z. Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition., 564-575. Vol. 21, Iss. 4 Nature neuroscience, 2018. (DOI: 10.1038/s41593-018-0110-8)
Seo, J S., Wei, J, Qin, Luye, Kim, Y, Yan, Z, and Greengard, P. Cellular and molecular basis for stress-induced depression., 1440-1447. Vol. 22, Iss. 10 Molecular psychiatry, 2017. (DOI: 10.1038/mp.2016.118)
Sun, L, Jiang, S, Tang, X, Zhang, Y, Qin, Luye, Jiang, X, and Yu, A C.. The Nanoscale Observation of the Three-Dimensional Structures of Neurosynapses, Membranous Conjunctions Between Cultured Hippocampal Neurons and Their Significance in the Development of Epilepsy., 7137-7157. Vol. 53, Iss. 10 Molecular neurobiology, 2016. (DOI: 10.1007/s12035-015-9588-1)
Qin, Luye, Liu, W, Ma, K, Wei, J, Zhong, P, Cho, K, and Yan, Z. The ADHD-linked human dopamine D4 receptor variant D4.7 induces over-suppression of NMDA receptor function in prefrontal cortex., 194-203. Vol. 95 Neurobiology of disease, 2016. (DOI: 10.1016/j.nbd.2016.07.024)
Kim, E, Woo, M S., Qin, Luye, Ma, T, Beltran, C D., Bao, Y, Bailey, J A., Corbett, D, Ratan, R R., Lahiri, D K., and Cho, S. Daidzein Augments Cholesterol Homeostasis via ApoE to Promote Functional Recovery in Chronic Stroke., 15113-26. Vol. 35, Iss. 45 The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015. (DOI: 10.1523/JNEUROSCI.2890-15.2015)
Duffney, L J., Zhong, P, Wei, J, Matas, E, Cheng, J, Qin, Luye, Ma, K, Dietz, D M., Kajiwara, Y, Buxbaum, J D., and Yan, Z. Autism-like Deficits in Shank3-Deficient Mice Are Rescued by Targeting Actin Regulators., 1400-1413. Vol. 11, Iss. 9 Cell reports, 2015. (DOI: 10.1016/j.celrep.2015.04.064)
Gu, Z, Cheng, J, Zhong, P, Qin, Luye, Liu, W, and Yan, Z. Aβ selectively impairs mGluR7 modulation of NMDA signaling in basal forebrain cholinergic neurons: implication in Alzheimer's disease., 13614-28. Vol. 34, Iss. 41 The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. (DOI: 10.1523/JNEUROSCI.1204-14.2014)
Yuen, E Y., Qin, Luye, Wei, J, Liu, W, Liu, A, and Yan, Z. Synergistic regulation of glutamatergic transmission by serotonin and norepinephrine reuptake inhibitors in prefrontal cortical neurons., 25177-85. Vol. 289, Iss. 36 The Journal of biological chemistry, 2014. (DOI: 10.1074/jbc.M114.567610)
Qin, Luye, Jing, D, Parauda, S, Carmel, J, Ratan, R R., Lee, F S., and Cho, S. An adaptive role for BDNF Val66Met polymorphism in motor recovery in chronic stroke., 2493-502. Vol. 34, Iss. 7 The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. (DOI: 10.1523/JNEUROSCI.4140-13.2014)
Bao, Y, Qin, Luye, Kim, E, Bhosle, S, Guo, H, Febbraio, M, Haskew-Layton, R E., Ratan, R, and Cho, S. CD36 is involved in astrocyte activation and astroglial scar formation., 1567-77. Vol. 32, Iss. 8 Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2012. (DOI: 10.1038/jcbfm.2012.52)
Qin, Luye, Kim, E, Ratan, R, Lee, F S., and Cho, S. Genetic variant of BDNF (Val66Met) polymorphism attenuates stroke-induced angiogenic responses by enhancing anti-angiogenic mediator CD36 expression., 775-83. Vol. 31, Iss. 2 The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011. (DOI: 10.1523/JNEUROSCI.4547-10.2011)
Kim, E, Tolhurst, A T., Qin, Luye, Chen, X Y., Febbraio, M, and Cho, S. CD36/fatty acid translocase, an inflammatory mediator, is involved in hyperlipidemia-induced exacerbation in ischemic brain injury., 4661-70. Vol. 28, Iss. 18 The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008. (DOI: 10.1523/JNEUROSCI.0982-08.2008)
Yu, A C., Liu, R Y., Zhang, Y, Sun, H R., Qin, Luye, Lau, L T., Wu, B Y., Hui, H K., Heung, M Y., and Han, J S.. Glial cell line-derived neurotrophic factor protects astrocytes from staurosporine- and ischemia- induced apoptosis., 3457-64. Vol. 85, Iss. 15 Journal of neuroscience research, 2007. (DOI: 10.1002/jnr.21345)
Li , H L., Li , Z, Qin, Luye, Liu, S, Lau, L T., Han, J S., and Yu, A C.. The novel neurotrophin-regulated neuronal development-associated protein, NDAP, mediates apoptosis., 1723-8. Vol. 580, Iss. 7 FEBS letters, 2006. (DOI: 10.1016/j.febslet.2006.02.022)
Chen, X Q., Qin, Luye, Zhang, C G., Yang, L T., Gao, Z, Liu, S, Lau, L T., Fung, Y W., Greenberg, D A., and Yu, A C.. Presence of neuroglobin in cultured astrocytes., 182-6. Vol. 50, Iss. 2 Glia, 2005. (DOI: 10.1002/glia.20147)
Chen, X Q., Liu, S, Qin, Luye, Wang, C R., Fung, Y W., and Yu, A C.. Selective regulation of 14-3-3eta in primary culture of cerebral cortical neurons and astrocytes during development., 114-8. Vol. 79, Iss. 1-2 Journal of neuroscience research, 2005. (DOI: 10.1002/jnr.20323)

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